ALAN EPPEL For decades, one of the most controversial issues within psychiatry has being whether or not antidepressants have any role to play in the treatment of bipolar disorder. Bipolar disorder consists of periods of depression and periods ..
VOL 2 #7 Natasha Snelgrove MD, FRCPC To much fanfare, and with an entire volume of the Canadian Journal of Psychiatry dedicated to these guidelines, the fourth iteration of the Canadian Network of Mood and Anxiety Treatment (CANMAT) Guideli..
VOL 2 #7 Resting state functional connectivity in women with bipolar disorder during clinical remission. Syan SK(1,)(2), Minuzzi L(1,)(2,)(3,)(4), Smith M(4), Allega OR(1,)(2), Hall GB(1,)(5), Frey BN(1,)(2,)(3,)(4). &nb..
Vol 3 #2 March 2018 Agomelatine is listed as a firstline medication for the treament of depression in a number of guidelines including Canadian Guidelines. This is the case eventhough Agomelatine is not approved for use in Canada..
The survey was sent to 105 psychiatrists working at an Academic Health Sciences Centre in Ontario Canada with multiple hospital sites.There were 41 responses which equals 39%. Survey Question Which antidepressant would you choose as your first..
Volume 5 # 1 January 2019 Alan Eppel MB, FRCPC McMaster University ABSTRACT Network Meta-analysis (NMA) is a powerful statistical tool that expands the methods of pairwise Meta-analysis. In this overview NMA is explain..
Vol 10 #6 Alan Eppel MB, FRCPC Introduction Bruxism although originally identified as a mechanical dental problem has more recently been recognized as a form of abnormal muscle movements. Bruxism is described as a repetiti..
A Caution Regarding Conclusions Based on Population-Based Analysis: Consider the Clinical Confounders
Journal of Psychiatry Reform Vol 11 # 7, May 2022 James A. Bourgeois, O.D., M.D.1,✉, Ana Hategan, M.D.2,iD Author information: 1 Clinical Professor, CL Psychiatrist, Chair, Department of Psychiatry, Baylor Scott & White H..
Considering the methodological limitations in the evidence base of antidepressants for depression: a reanalysis of a network meta-analysis
BMJ Open 2019;9:e024886. doi: 10.1136/bmjopen-2018-024886 Reprinted in the Journal of Psychiatry Reform Vol 9 #16. November 14, 2022 under the Creative Commons CC-BY-NC 4.0 license Authors Klaus Munkholm, Asger Sand Paludan-Müller, ..
Journal of Psychiatry Reform Vol 9 #17. November 15, 2022 Author Alan Eppel MB, MRCPsych, FRCPC The author has no conflicts of interest. In this edition of the journal we have reprinted a Danish Cochrane reanalysis of a meta-analysis conducted..